The Science Behind Laxogenin: What Do We Know So Far?

Laxogenin is a natural anabolic compound that was first isolated from the plant Smilax Sieboldii in 1992.

It has been shown to have potent anabolic effects in animal studies, making it a popular ingredient in sports supplements. Laxogenin works by increasing protein synthesis and improving nitrogen retention, both of which are critical for building muscle mass.

This product is also known for its ability to improve recovery from exercise, making it a valuable tool for athletes and bodybuilders looking to maximize their gains.

While laxogenin is a relatively new compound, it has quickly become one of the most popular ingredients in sports supplements due to its potent anabolic effects.

What is Laxogenin?

Laxogenin is a chemical found in plants that is taken by mouth to build muscle and increase strength. Laxogenin is similar to another chemical called 5-alpha-hydroxy laxogenin, and both are sold as medicine.

In dietary supplements, you will often find 5a-hydroxy laxogenin, which is a synthetic version of the compound. Many people often confuse it for some type of prohormone, but it’s not.

It doesn’t interfere with the body’s natural hormone production, unlike prohormones do. This makes it a useful and supposedly safe muscle-building compound for athletes that don’t want to turn to dangerous performance-enhancers.

• Laxogenin is a plant-based chemical that could potentially offer some benefits for athletes looking to improve their performance without resorting to dangerous drugs.

Benefits of Laxogenin

There are many benefits associated with laxogenin use. Perhaps the most notable is its ability to accelerate muscle recovery.

This means that athletes can train harder and more frequently without experiencing the post-exercise muscle soreness that often slows progress.

In addition, laxogenin has been shown to reduce cortisol levels, which can help minimize physical and mental fatigue, allowing athletes to achieve peak performance for longer periods of time.

Furthermore, laxogenin is believed to stimulate protein synthesis, resulting in faster strength gains and improved resistance to physical stress.

Laxogenin can be used by both men and women without any reported side effects, making it a safe and versatile choice for athletes of all levels. There is no need to restrict use to a short period of time; in fact, using laxogenin on a continual basis may provide even better results.

What are the benefits of laxogenin for bodybuilding? 

1. Laxogenin has been shown to be effective in building muscle mass. It can help you burn fat and recover faster, which means you can train harder and achieve better results. 
2. It is a natural plant compound that has been shown to have anabolic properties, meaning it helps the body build muscle. 
3. Laxogenin can help you burn fat while preserving muscle mass, which is a common problem with many weight loss programs. 
4. It also helps reduce inflammation and speeds up recovery, which means you can train more often and achieve better results. 
5. Finally, laxogenin has been shown to improve performance, making it a valuable supplement for athletes of all types.

The Science Behind Laxogenin

Some dietary supplements that are marketed for anabolic benefits or performance enhancement contain substances that are not approved and might lack quality controls.

The inclusion of substances or techniques in the World Anti-Doping Agency’s banned list is based on medical or scientific evidence for athletes. Laxogenin is a synthetic spirostane-type steroid that can be found in some dietary supplements.

There is no evidence that laxogenin has anabolic or androgenic activity thus far. In two in vitro bioassays, we studied its androgenic potential. While the yeast androgen screen revealed no activity, 5α-hydroxy-laxogenin was able to trans-activate the androgen receptor in human prostate cells.

This does not necessarily mean that it would also have anabolic effects in humans. More research is needed to understand the potential effects of laxogenin on human health and performance.

Protein synthesis is the process by which cells build proteins, and it is a key factor in muscle growth. Nitrogen retention is another important process for muscle growth, as it helps the muscles hold onto amino acids, which are the building blocks of protein.

Laxogenin has been shown to increase protein synthesis and nitrogen retention in animal studies, both of which are critical for building muscle mass.

Clinical Studies:

https://link.springer.com/article/10.1007/s00204-022-03283-5

https://www.scielo.br/j/jbchs/a/Hdcq7kHnKQ3nB6gvNYkyhxc/?lang=en

https://pubmed.ncbi.nlm.nih.gov/1369386/

Laxogenin Mechanism of Action

The mechanism of action of laxogenin is not fully understood, but it is believed to activate an anabolic protein and the fight-or-flight response. It is also believed to have adaptogenic qualities, which means that it helps to normalize and improve the body’s stress response.

Additionally, laxogenin is thought to help reduce cortisol and stress levels, limit protein breakdown, improve injury recovery, reduce pain, and improve cholesterol levels.

While the exact mechanism of action is not known, it is clear that laxogenin has a number of potential benefits for athletes.

Dosage and Administration

Laxogenin is typically taken in capsule form, with the recommended dose being 100-200 mg per day. It can be taken with or without food, and there is no need to cycle it.

Laxogenin can be used for long periods of time without any reported side effects, making it a safe and versatile choice for athletes of all levels.

Possible Side Effects

There are no known side effects associated with laxogenin use. This is likely due to the fact that it is a plant-based substance that is not known to interact with any medications or supplements.

As with all supplements, it is recommended that you speak with a healthcare professional before starting use, especially if you have any existing medical conditions.

What does Laxogenin do to your body?

• Laxogenin Plant hormone:

Laxogenin is a plant hormone that belongs to the brassinosteroid family. It stimulates protein synthesis, which helps to prevent break down of muscle proteins. Additionally, it helps to improve nitrogen retention, which is important for muscle growth.

• Member of brassinosteroid family:

Laxogenin is a member of the brassinosteroid family, which are a group of hormones that play an important role in growth and development.

• Stimulates protein synthesis:

It stimulates protein synthesis, which helps to maintain muscle mass and prevents muscle wasting.

• Prevents breakdown of muscle proteins:

Laxogenin encourages protein synthesis, which leads to less breakdown of muscle proteins. This helps to maintain or build muscle mass, especially in times of stress or illness when muscle loss can occur.

Laxogenin vs Ecdysterone

There are many different compounds found in nature that offer potential benefits for athletes and bodybuilders. Two of these compounds are laxogenin and ecdysterone.

Laxogenin, a natural anabolic compound originating from the Smilax Sieboldii plant, could potentially be a valuable supplement for bodybuilders. This is due to the potent anabolic effects observed in animal studies.

Ecdysterone is a one-of-a-kind, naturally occurring chemical. It’s also known as a plant steroid since it has a structure that is comparable to human testosterone.

The two most common plants it is derived from are spinach and quinoa. Researchers found that ecdysterone could potentially increase lean muscle mass and athletic performance. However, there is not enough evidence currently to support these claims.

Laxogenin has a number of potential benefits for athletes, including increased protein synthesis, improved nitrogen retention, reduced cortisol levels, and enhanced recovery from exercise. Ecdysterone also has potential benefits for athletes, but more research is needed to confirm these effects.

At this time, there is no clear winner between laxogenin and ecdysterone. However, both compounds show promise as safe and effective supplements for athletes.

Laxogenin vs Anavar:

Anavar is a synthetic anabolic androgenic steroid (AAS) that is derived from testosterone. Laxogenin is not a prohormone or AAS and poses no side effect of liver toxicity. Both men and women can take laxogenin. 

The benefits of laxogenin for bodybuilding include building muscle mass, burning fat, reducing recovery time, and enhancing performance. Laxogenin is a natural anabolic compound while Anavar is a synthetic AAS. Laxogenin has been shown to have potent anabolic effects in animal studies, making it a potentially useful supplement for bodybuilders. Anavar has been shown to be effective in increasing strength and muscle mass in human studies, making it a popular choice among athletes.

Laxogenin may be a safer alternative to Anavar for athletes and bodybuilders who are looking to increase strength and build muscle mass. However, more research is needed to confirm the effects of laxogenin in humans.

If you are considering using laxogenin or Anavar for bodybuilding, it is important to speak with a healthcare professional first to evaluate the risks and benefits. Laxogenin may be a safer alternative to Anavar for bodybuilding, but more research is needed to confirm its efficacy in humans.

Is Laxogenin legal or illegal?

Yes, Laxogenin is legal. You can buy it without a prescription and there are no restrictions on its use.

Pros:

1. Laxogenin is a natural substance that is found in the plant Smilax Sieboldii. This means that it is not synthetic and therefore has a lower chance of causing side effects. 

2. It has been shown to increase strength and improve recovery times and acts as an excellent alternative to testosterone boosters. 

3. Laxogenin does not require injections, which can be painful and cause other side effects.

4. Laxogenin is non-toxic and has been studied for its potential medical use in cancer, tissue damage, and diabetes.[1, 2, 3]

5. Laxogenin is a legal supplement that can be purchased without a prescription.

6. There is less risk of side effects than with other steroids or prohormones.

7. Laxogenin can be stacked with other supplements for even better results.

Cons:

1. There is limited clinical testing on laxogenin and most of the information available is based on animal and cell studies.

2. The safety profile of laxogenin is unfinished and there may be unknown side effects associated with its use.

3. There is no clinical testing to prove the safety or efficacy of laxogenin as a performance enhancer.

4. Laxogenin is relatively new to the market and there is no long-term data on its effects.

Laxogenin is available in supplements such as liquids, powders, and capsules.

The form of laxogenin that is appropriate to use in different situations depends on the person’s needs.

Liquid laxogenin

• It is best for people who want a fast and easy way to take the supplement.
• Liquid laxogenin is the most convenient form to take as it is already in a liquid form and does not require any preparation.
• It can be taken with or without food and it is easy to mix with drinks. The liquid form is also convenient for traveling.
• It is the easiest to use and it is quickly absorbed by the body. 
• The downside to using liquid laxogenin is that it can be messy.

Powder laxogenin

• Powder laxogenin is the most affordable.
• It is best for people who are interested in taking a higher dose of the supplement. It is also a good choice for those who want to mix the supplement with their food or drink. Some people may not like the taste.
• The downside to using powder laxogenin is that it can be difficult to measure the correct dosage.
• It can be difficult to measure the correct dosage and it is not as portable as the other forms.

Capsule laxogenin

• Capsule laxogenin is best for people who do not like taking liquids or powders.
• Capsules are also a good choice for those who want to take their laxogenin supplement on the go. The downside is that they can be bulky to carry with you when you’re traveling.
• It is easy to swallow and does not have any taste.
• Capsules could provide a slow release of laxogenin over an extended period of time.

Fore example you could take a look at Hi-tech laxogenin

The key ingredient is always the same, so it’s up to you to select the product that best fits your lifestyle.

According to USADA about Laxogenin:

Laxogenin is an ingredient that has recently been found to be included illegally in dietary supplements. This ingredient has not been approved by the FDA as a lawful dietary ingredient, and as such, its use may result in anti-doping rule violations.

Athletes and others subject to anti-doping rules are advised to avoid supplements containing this ingredient.

There is no concrete evidence to suggest that 5-Alpha-Hydroxy-Laxogenin has any negative health effects. However, as the ingredient has not been tested on humans, it is unclear what the potential side effects could be. Additionally, there are two more good reasons to avoid this ingredient:

“5-Alpha-Hydroxy-Laxogenin might indicate the presence of an undeclared PED in a product.”

“The FDA considers it unlawful in dietary supplements.”

https://www.usada.org/spirit-of-sport/education/illegal-ingredient-5-alpha-hydroxy-laxogenin-supplements/

https://www.fda.gov/food/cfsan-constituent-updates/fda-sends-warning-letters-multiple-companies-illegally-selling-adulterated-dietary-supplements

Conclusion

Given the information above, it is important to do your own research before deciding whether or not to buy laxogenin.

There are a number of potential side effects associated with its use, and as the ingredient has not been tested on humans, it is unclear what these could be.

Additionally, laxogenin is an illegal ingredient in dietary supplements and may result in anti-doping rule violations.

• However, there are two more good reasons to avoid this ingredient: “5-Alpha-Hydroxy-Laxogenin might indicate the presence of an undeclared PED in a product” and “The FDA considers it unlawful in dietary supplements.”

If you still decide to take laxogenin despite all of these risks, make sure you purchase from a reputable source that discloses all ingredients on their label.

Alternatively, there are less controversial supplement options available that have been clinically tested and shown to be safe and effective.